College football analyst David Pollack predicts Oregon will defeat USC in Week 13, highlighting the Ducks’ dominant defense, balanced offense, and USC’s struggles to pressure quarterback Dante Moore in a key playoff matchup.

One of the most intriguing and consequential games of the college football weekend kicks off Saturday afternoon in Eugene, OR where the 6th-ranked Ducks host the No. 16 Trojans of USC (8-2). There are significant College Football Playoff implications for both teams.

The Week 13 slate is a bit of a calm before the storm, but there are still quite a few big-time matchups on the docket.

The week 13 matchup between the Oregon Ducks and the USC Trojans will be the 65th meeting between the two longtime foes. The rivalry between Oregon and USC ext

Throughout the 2025 campaign, the Oregon Ducks have continued making their rounds of meeting Big Ten opponents for the first time as a member of the conference, often with select matchups prior to then. But in Week 13 against the USC Trojans, that won't be the case.

Whose defense will step up in the USC-Oregon game? USA TODAY's Jordan Mendoza and The Register-Guard's Alec Dietz break it down.

Best College Football Playoff contender betting picks at FanDuel: Combine these three picks involving Texas-Arkansas, USC-Oregon, BYU-Cincinnati for a +679 payout

The last time these teams met as ranked foes was 2015, which was the 10th straight such meeting. They split those 10 games.

Joel Klatt joins Colin Cowherd to discuss Miami’s issue with Notre Dame being ranked higher than them, whether or not Texas has a chance at the playoffs after losing 35-10 to Georgia, and USC’s odds of beating Oregon.

USC football 's game this Saturday against Oregon represents an unofficial elimination game. Win, and the Trojans will be in position to secure a College Football Playoff berth with a win against UCLA. Lose, and the USC will find itself in another bowl game that few fans care about.