We recently developed base editing, a genome-editing approach that enables the programmable conversion of one base pair into another without double-stranded DNA cleavage, excess stochastic insertions ...

DNA sequencing refers to the process of identifying the order of bases in a strand of DNA. DNA is comprised of nucleotides, with each nucleotide consisting of a sugar, a phosphate group and a base.

Scientists from Oxford's Radcliffe Department of Medicine have achieved the most detailed view yet of how DNA folds and ...

Ultraconserved elements are DNA sequences, hundreds of base pairs long, that are 100-percent identical in mice, rats and humans. Their perfect conservation for over 80 million years was thought due to ...

The genetic alphabet contains four letters. Although our cells can readily decipher our genetic molecules, it isn't so easy for us to read a DNA sequence in the laboratory. Scientists require complex, ...

The building block of life is often heralded as the cornerstone of a new generation of electronic devices and computers, but the electronic properties of DNA remain highly controversial. 1 Back to ...

The laws of inheritance are quite unknown,” Charles Darwin acknowledged in 1859. The discovery of DNA’s shape altered how we ...

The DNA sequence of a 196 base pair (bp) region of the acetolactate synthase (ALS) genes of three weed species, kochia, prickly lettuce, and Russian thistle, was determined. This region encompasses ...