在生命科学的宏伟叙事中，DNA修复常常被描绘成一个英雄般的篇章。细胞内精密的分子机器夜以继日地巡逻，一旦发现DNA序列上出现断裂，尤其是最凶险的双链断裂 (Double-Strand Breaks, ...

*仅供医学专业人士阅读参考本周一，《自然》杂志的一篇新闻报道显示，纽约一家名为曼哈顿基因组的科技公司，宣布要通过对人类胚胎进行基因编辑来预防遗传病[1]。此消息一出来，就引起很多科学家的担忧，毕竟贺建奎在2018年发布的“世界首个基因编辑婴儿已诞生” ...

Cavefish exhibit resilience to chronic sleep loss and tolerate elevated DNA damage and reduced DNA repair responses without compromising healthspan or longevity.

因纽特人一直保持着捕猎弓头鲸（Balaena mysticetus，一种大型须鲸）的古老传统，他们认为这种鲸鱼“能活人类的两辈子”。后续的相关科学研究都证实了弓头鲸的最长寿命超过 200 ...

Failure to repair DNA damage can result in DNA lesions and mutations that are a driving factors in cancer development. Recent work has identified a function for DNA damage repair mechanism beyond ...

Artios Pharma, which looking for newer targets that, like PARP inhibitors, affect the way tumors fix themselves, said its ...

肠道作为人体的 “代谢超级器官”，其健康状态与衰老进程息息相关。随着年龄增长，肠道菌群失衡、肠道屏障功能受损、DNA损伤累积等问题接踵而至，进而引发全身性慢性炎症、免疫功能下降等 “衰老相关病症”，甚至牵连大脑、骨骼等其他器官健康。此次发表的研究，正是瞄准这一核心痛点，深入探索肠道衰老的调控机制，为开发针对性的长寿干预方案提供了全新思路。

Learn more about bowhead whales and how they routinely see out their 200th birthday — and this DNA-repair protein might just ...

Researchers discovered that bowhead whales achieve extraordinary longevity and cancer resistance through highly efficient and precise DNA repair mechanisms. A whale-specific protein, CIRBP, enhances ...

Nutritious food regular exercise quality sleep hydration and stress control are the simple life habits that can protect DNA ...