Gene transfer agents (GTAs) are unique, phage‐like particles produced by various Alphaproteobacteria that mediate the horizontal transfer of genetic material. Unlike conventional bacteriophages, GTAs ...

Antibiotic resistance is widely recognized as one of the most urgent public health challenges of the twenty first century.

A team led by Tappei Mishina at the RIKEN Center for Biosystems Dynamics Research (BDR) has discovered that parasites manipulate their hosts using stolen genes that they likely acquired through a ...

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems. Now an interdisciplinary ...

A fundamental challenge for cystic fibrosis (CF) gene therapy is ensuring sufficient transduction of airway epithelial cells to achieve therapeutic correction. Vehicles such as lysophosphatidylcholine ...

Antibiotic resistance is widely recognized as one of the most urgent public health challenges of the twenty first century.

One problem in gene therapy is that not all genes transfer equally well into the target cells. Researchers have now developed a flexible method to transfer large genes efficiently and without ...

Laboratories are loading mammalian cells and tissues with exogenous DNA more routinely and more successfully than ever before. The means available to deliver the DNA--lipofection, transduction, ...

Around the globe, heart disease remains one of the top causes of death. Once patients begin to suffer from serious heart ...