Preview the NFL Week 12 Detroit Lions vs. New York Giants game with insights, current betting odds including moneyline, spread, over/under and more.

Is it time Myles Garrett got a new nickname?Myles the Menace? Myles the Monster? Myles … the all-time single-season sack leader?Monikers aside, Garrett is on a tear this season. He has a league-leading 15 sacks through 10 games for 2-8 Cleveland.

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While Los Angeles Rams quarterback Matthew Stafford (+150) and New England Patriots quarterback Drake Maye (+185) remain at the top, the rest of the MVP race saw plenty of shake-ups.

What to know: The Chiefs have won the AFC West nine straight times. Is this the year that streak ends? Denver is 9-2 and the Chargers are 7-4, and both teams have one win over K.C. already, meaning the 5-5 Chiefs are well behind two teams in their own division.

Here's a look at the latest No. 1 pick odds for the 2026 NFL Draft from DraftKings. Simpson threw a pick-6 and also failed to convert on a fourth down to keep a potential game-winning drive alive. Couple those moments with Mendoza throwing for 299 yards and four touchdowns and you can see why the gap has narrowed.