The San Francisco 49ers defeated the Arizona Cardinals 41-22 on Sunday at State Farm Stadium, and head coach Kyle Shanahan ...

The San Francisco 49ers will hold three full practices this week as they prepare for their Week 11 matchup against the ...

The San Francisco 49ers entered their second matchup against the Arizona Cardinals as favorites and won. Here were the worst ...

Following a “frustrating” six-week absence due to a toe injury,  49ers quarterback Brock Purdy returned to the lineup in ...

NFL Nation reporters break down the good and bad for each OC/playcaller and peg the key to success the rest of ...

The Arizona Cardinals will be without one of their top playmakers when they face the San Francisco 49ers this Sunday at State ...

The San Francisco 49ers and Carolina Panthers are in a race for a playoff spot, but the 49ers are favored big in their Week ...

The 49ers quarterback threw three touchdowns, including two to George Kittle, in a blowout win over the Arizona Cardinals ...

Shanahan breaks down the latest 49ers injury updates after the Week 11 win over the Cardinals, including key statuses for ...

The San Francisco 49ers blew out the Arizona Cardinals, but there was a lot happening in the Week 11 matchup. Here are ...

BOX SCOREQuarterback Brock Purdy’s return to the 49ers’ starting lineup on Sunday went as well as San Francisco could have ...

The San Francisco 49ers officially listed quarterback Brock Purdy as questionable for Sunday's game against the Los Angeles ...