Circ-EGFR was identified as a novel predictive biomarker for cetuximab efficacy in KRAS wild-type metastatic colorectal ...

The endoplasmic reticulum (ER) and mitochondria form contacts that support communication between these two organelles, including synthesis and transfer of lipids, and the exchange of calcium, which ...

Low levels of TP‐primed initiation activity can be obtained in the absence of protein p6 (Blanco et al, 1986). Under these conditions, Spo0A did not have a significant effect (not shown) indicating ...

In this workshop we work on the principles, practicalities and strategies of writing a scientific research article. Topics covered include understanding the structure and content of a manuscript, ...

Over the past decade, several tumor-based predictors of cetuximab efficacy have been identified, yet most function as ...

The photoreceptors required for post‐translational regulation of CO have been characterized. Mutations in the genes encoding the photoreceptors phytochrome A (phyA) and cryptochrome 2 (cry2) delay ...

Each journal is staffed by professional editors who work in collaboration with one another and our international Editorial Advisory Boards of leading scientists. Please feel free to contact any of the ...

While such loss‐of‐function mutagenesis is a powerful approach to the genetic dissection of signal pathways (Glazebrook, 2001), many genes cannot be uncovered in this way because of lethal effects or ...

MicroRNAs (miRNAs) constitute a novel, phylogenetically extensive family of small RNAs (∼22 nucleotides) with potential roles in gene regulation. Apart from the finding that miRNAs are produced by ...

Posttranslational modifications expand the diversity of the proteome enormously, with protein glycosylation being the most abundant and diverse form of modification serving different functions for ...

The RNA‐binding protein HuR regulates the stability and translation of numerous mRNAs encoding stress‐response and proliferative proteins. Although its post‐transcriptional influence has been linked ...

Mutations in fused in sarcoma (FUS) are a cause of familial amyotrophic lateral sclerosis (fALS). Patients carrying point mutations in the C‐terminus of FUS show neuronal cytoplasmic FUS‐positive ...