Gap junctions are specialised intercellular channels that facilitate direct communication between adjacent cells by allowing the regulated exchange of ions, second messengers and small metabolites.

Rat heart and other organs contain mRNA coding for connexin43, a polypeptide homologous to a gap junction protein from liver (connexin32). To provide direct evidence that connexin43 is a cardiac gap ...

This is a preview. Log in through your library . Abstract By using two ultrarapid freezing techniques, we have captured the structure of rat and rabbit cardiac gap junctions in a condition closer to ...

Researchers studying a critical stage of pregnancy – implantation of the embryo in the uterus – have found a protein that is vital to the growth of new blood vessels that sustain the embryo. Without ...

Scientists have uncovered a key role for the protein “Frazzled” in building and maintaining the rapid neural connections that allow fruit flies to react in milliseconds.

TNBCs rely on fatty acid oxidization (FAO) to fuel tumor growth by breaking down surrounding adipose tissue through lipolysis. Gap junctions, particularly involving GJB3 and connexin 31 (Cx31), ...

Adeno-associated virus vector containing an adenine base editor provides an effective strategy to treat hereditary hearing loss caused by the R75W mutation. Moreover, this gene editing technology can ...