In a successful transplant in a man with brain death, scientists prevented the immune system from attacking a genetically ...

A pig kidney with one genetic change functioned in a brain-dead human for 61 days, more than doubling previous records.

Findings also confirmed that a pig kidney can effectively serve as a replacement for a human kidney. Researchers have ...

Researchers have uncovered and then overcome an obstacle that has led to the failure of pioneering efforts in ...

Penn and CHOP researchers want to develop urea cycle disorder treatments using CRISPR gene-editing therapy. Get unlimited access to Inquirer.com and The Inquirer App, plus 5 articles each month to ...

The successful treatment in a brain-dead man could be used in living people, to prevent the immune system attacking donor organs.

Movies have always played up the mad scientist trope, but real-life labs have carried out experiments that make fiction look ...

Beam Therapeutics Inc. (Nasdaq: BEAM), a biotechnology company developing precision genetic medicines through base editing, today announced that the company will present updated safety and efficacy ...

It is a deep question, from deep in our history: when did human language as we know it emerge? A new survey of genomic evidence suggests our unique language capacity was present at least 135,000 years ...

The transplanted portion of the genetically modified pig liver was removed after 38 days, and the patient, who had advanced liver cancer and cirrhosis, died several months later. By Roni Caryn Rabin ...

The contribution of genetics to the variability in people’s metabolism has remained largely unknown. This is, in part, because genetic studies of human metabolism have been limited in scale and ...