Gap junctions are specialised intercellular channels that facilitate direct communication between adjacent cells by allowing the regulated exchange of ions, second messengers and small metabolites.

Developmental biologists have discovered that during egg development in fruit flies, intercellular gaps open between epithelial cells in a controlled way at the points where three cells meet. This ...

Elevation of the calcium concentration in human keratinocyte culture rapidly induces the redistribution of E-cadherin, P-cadherin, vinculin, β1 integrin, and desmoplakin to the cell-cell borders.

The formation of a cancer is proven to be a multi-stage, multi-mechanism process by animal and human studies. As a definite carcinogen, the role of Helicobacter pylori (H pylori) in the formation of ...

Northwestern Medicine investigators have discovered a novel mechanism linking an intercellular adhesion molecule with genetic inflammatory skin diseases, according to findings published in the Journal ...

Radiation Research, Vol. 123, No. 3 (Sep., 1990), pp. 241-251 (11 pages) Carcinogenesis is a multistep process, involving the irreversible conversion of a stem cell to a ...

With the increasing exploration of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the causative pathogen of coronavirus disease 2019 (COVID-19) pandemic – it has become clear that ...

Within multicellular organisms, cells build connections with each other forming cell layers that cover the surfaces of tissues and organs and separate structures in the body. For example, the skin ...