A 79-year-old man was admitted to a hospital in Guangzhou, China, with progressive dyspnea and edema. Echocardiography and ...

The benefit of beta-blockers after myocardial infarction in patients with a preserved left ventricular ejection fraction ...

Icotrokinra, a targeted oral peptide that selectively binds the interleukin-23 receptor, is under investigation for the ...

Patients with severe hypertriglyceridemia have an increased risk of acute pancreatitis. The efficacy and safety of olezarsen, ...

Despite guideline recommendations, evidence for the use of non–vitamin K antagonist oral anticoagulant (NOAC) monotherapy in ...

Personalized therapies hold tremendous promise but challenge traditional models of drug and biologic development. The FDA outlines a path to market entry for products where a randomized trial is no ...

Both tobevibart (a monoclonal antibody) and elebsiran (a small interfering RNA) target hepatitis B virus surface antigen ...

Explore this issue of The New England Journal of Medicine (Vol. 0 No. 0).

U.S. hospitals have begun responding to the implementation of health care reform by accelerating their hiring of physicians. Understanding the economics of these decisions will help physicians to a ...

State Medicaid agencies can now apply to participate in a new model that supports voluntary, outcomes-based agreements between Medicaid programs and manufacturers of gene therapies for sickle cell ...

Angiopoietin-like protein 3 (ANGPTL3) inhibits lipoprotein and endothelial lipases. ANGPTL3 loss-of-function genetic variants are associated with decreased levels of low-density lipoprotein ...