New research shows a therapy that’s been used for cancer patients may help people with lupus go into remission.

The Harlem Globetrotters celebrate their 100th anniversary with a tour, including three games in Indiana during the month of ...

A Fort Wayne Community Schools bus driver has been taken into custody after leading Fort Wayne Police Department officers on a pursuit.

The U.S. stock market is swinging through more unsettled trading. The S&P 500 added 0.2% Wednesday after veering between a ...

Notre Dame running back Jeremiyah Love appreciates hearing his name in the Heisman Trophy conversation. He’s just focused on ...

Indiana Governor Mike Braun discusses entrepreneurship, and addresses the state senate's decision on redistricting.

The prosecution of former FBI Director James Comey hit another hurdle Wednesday as the Justice Department acknowledged a possible lapse in how the case was presented to a federal grand jury for ...

The Indiana Music History Project expands its Oral History Project, capturing the stories of influential Indiana musicians across various genres.

Colts head coach Shane Steichen announces the return of Charvarius Ward and Jaylon Carlies to practice. Ward still needs to ...

Approximately 300 Indiana National Guard soldiers are being deployed to Washington D.C. to support safety measures in the nation's capital.

Lots of clouds today with temperatures below normal. More rain returns Friday with temperatures back into the 50s.

LVIV, Ukraine (Reuters) -Nineteen people were killed in a heavy overnight Russian missile and drone attack that struck an ...