Artios Pharma, which looking for newer targets that, like PARP inhibitors, affect the way tumors fix themselves, said its ...

Recent research has shed light on the complex processes that cells use to maintain the quality of mitochondrial DNA (mtDNA) ...

Scientists identified a small molecule that interrupts a harmful protein pair linked to diabetic inflammation and tissue ...

Cavefish exhibit resilience to chronic sleep loss and tolerate elevated DNA damage and reduced DNA repair responses without compromising healthspan or longevity.

Immunotherapy—could that be an option for me, doctor?” is a question frequently asked by patients with colorectal cancer. The ...

Scientists discover that bowhead whales’ CIRBP protein enhances DNA repair, offering potential breakthroughs in anti-aging ...

Aging brings about a range of changes—often unwelcome—to our bodies: sagging skin, graying or thinning hair, and a decline in muscle strength and ...

From cancer-resistant mole rats to 200-year-old whales, evolution has equipped long-lived species with unique biological ...

The atlas integrates single-cell and bulk data across hundreds of liver samples, including gene expression, chromatin accessibility, and DNA methylation, paired with cfDNA methylation from matched ...

Innovative Team Science programmes at the MRC Laboratory of Medical Sciences will tackle big questions about ageing, sex differences and health. The transdisciplinary teams will take a 360 view of ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Poly(ADP-ribose) polymerase 1 (PARP1) is one ...

A body that weighs as much as a small airplane should face steep odds against cancer. You may expect that from a creature ...