Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Ubiquitination of the C-terminus of histone ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

Get powerful, A Detailed 3d Animation Of A Double Helix Dna Structure The Animation Rotates And Showcases The Intricate Details Of The Molecule pre-shot video to fit your next project or storyboard.

Human exonuclease 1 (EXO1), a member of the structure-specific nuclease family, plays a critical role in maintaining genome stability by processing DNA double-strand breaks (DSBs), nicks, and ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...

Accurate genome duplication is essential for all living cells. In Escherichia coli and most other bacteria, a circular chromosome is replicated bidirectionally at high speed. Two replisomes, assembled ...

This valuable descriptive manuscript builds on prior research showing that the elimination of Origin Recognition Complex (ORC) subunits does not halt DNA replication. The authors obtain solid data ...

The MRE11/RAD50/NBS1 (MRN) complex plays multiple roles in the maintenance of genome stability, requiring coordinated regulation of its activities, though the underlying mechanisms are not fully ...

The discovery of DNA ligase by the Gellert, Lehman, Richardson, and Hurwitz teams in 1967 was a breakthrough in molecular biology. These essential enzymes maintain genome integrity and play a vital ...

A University of Iowa-led study uncovered a unique double-ring structure of the DNA repair protein RAD52 that plays a critical role in protecting stalled DNA replication in cancer cells with repair ...