DNA repair is essential for the maintenance of genomic stability and its failure can lead to human disease. Various DNA repair systems exist, such as base excision repair, nucleotide excision repair, ...

Researchers have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging. Researchers at ...

David Liu and Richard Merkin of the Broad Institute of MIT and Harvard, along with Columbia professor Sam Sternberg, have developed a new, targeted means of inserting entire genes into human DNA ...

WHEN THE first draft of the DNA sequence that makes up the human genome was unveiled in 2000, America’s president at the time, Bill Clinton, announced that humankind was “learning the language with ...

Human DNA in its natural state inside cells (left) compared to eight hours after being infected with HSV-1 (right). The virus compacts the human genome’s size significantly and moves it towards the ...

For decades, large stretches of human DNA were dismissed as "junk" and considered to serve no real purpose. In a new study published in Cell Genomics, researchers at Lund University in Sweden show ...