Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

KYOTO – An international team of researchers has taken an important step toward understanding how gene expression is controlled across the human genome. A new study has comprehensively analyzed ...

Gene regulation is the fundamental process through which cells control the expression of genetic information, ensuring that genes are activated at the appropriate time and in the correct context. In ...

In biology classrooms, we often learn that genes are transcribed into mRNA, which is then translated into proteins—a tidy, linear process. But gene expression in living cells is far more intricate, ...

Although heart cells and skin cells contain identical instructions for creating proteins encoded in their DNA, they're able ...

Genes are regulated by complex interactions involving transcription factors, DNA regulatory regions, and epigenetic modifications which alter chromatin structure. Modifications to chromatin regulate ...

Please provide your email address to receive an email when new articles are posted on . The Nobel Assembly at Karolinska Institutet in Sweden announced the honor ...

The immune system faces a delicate balancing act: it must be aggressive enough to fight infections and cancer, yet restrained ...

Understanding how cells turn genes on and off is one of biology's most enduring mysteries. Now, a new technology developed by chemist Brian Liau and his collaborators at Harvard offers an ...

Researchers from the National University of Singapore (NUS) have revealed that diet and exercise can change gene regulation in the skeletal muscle of East Asians, highlighting the critical role of ...

A new genome editing tool—minimal versatile genetic perturbation technology (mvGPT)—can achieve simultaneous and orthogonal gene editing and gene regulation in human cells. The coming together of ...