Tipoff is set for 8 p.m. ET. Boston is a 1.5-point home favorite in the latest 76ers vs. Celtics odds, while the over/under is 230.5. Before making an Celtics vs. 76ers picks, check out the NBA predictions and betting advice from the SportsLine Projection Model.

Boston can steal a win if they play well, but limiting transition and the twin punches of Tyrese Maxey and VJ Edgecombe will be key.

Tyrese Maxey scored 21 points and Kelly Oubre Jr. scored the go-ahead basket on a follow with 8.7 seconds left to lead the Philadelphia 76ers to a 102-100 win over the Boston Celtics.

The Philadelphia Sixers started the season on a high, winning 4-0, but things haven’t been good lately as they lost 4 of their last 6 matchup. Now, they face the Boston Celtics, who are traveling to Philadelphia for a classic Eastern Conference showdown on Tuesday night.

The Boston Celtics and Philadelphia Sixers prepare for a November 11, 2025, clash. Jayson Tatum is out for the Celtics. Joel Embiid is cleared but not at full strength for the Sixers. Paul George and Johni Broome are sidelined.

Joel Embiid continues to deal with right knee soreness and received a concerning update after being ruled out vs. the Celtics on Tuesday.

This week, Coast 2 Coast Tuesday on November 11 features a pair of must-watch games, and it all tips off in Philly, where the 76ers host the Celtics beginning at 8 p.m. ET on NBC. The game will also stream live on Peacock. That's followed by the Denver Nuggets at the Sacramento Kings at 11 p.m. ET.