The Jacksonville Jaguars have a key Week 12 matchup, with their road contest against the Arizona Cardinals having the potential to be the

Everything you need to know about the NFL match between Arizona Cardinals and Jacksonville Jaguars, as well as kick-off time and team news

Defensively, Jacksonville is working through a few injuries with defensive end Travon Walker (knee) missing back-to-back practices, while cornerback Jarrian Jones was again limited in Thursday's practice due to a quadricep injury. Here's Jacksonville's latest injury news ahead of their Week 12 game against the Cardinals.

The Arizona Cardinals are designating running back Trey Benson to return from injured reserve, but Marvin Harrison Jr. is out against the Jaguars.

USA Today's NFL experts make their picks for a Week 12 showdown between the Arizona Cardinals and Jacksonville Jaguars

Veteran quarterback Jacoby Brissett’s 10-year NFL career has included several twists and turns. He has been a project, a starter, a backup, a Super Bowl champion and soldiered through some mediocre seasons.

On Sunday at 1 p.m. ET at M&T Bank Stadium, Lamar Jackson and the Baltimore Ravens match up with the New York Jets in Week 12. Jackson completed 14-of-25 passes (56.0%) for 193 yards, no passing touchdowns,

Find single game tickets to the Jacksonville Jaguars vs. Arizona Cardinals NFL Week 12 matchup on Sunday, November 23, 2025 at State Farm Stadium.