The San Francisco 49ers have some talented coaches on their staff and some might end up running their own teams someday.

From win streaks to highlight reel-worthy plays, these are the moments that have defined the last decade of Big Game.

Selected from Alabama with the 12 th choice in the NFL Draft on April 24, Booker played every offensive snap in his debut on Sept. 4. The Cowboys scored on all four of their first-half possessions but ...

Mac Jones could become one of the more intriguing names on the offseason trade market. The quarterback impressed during his ...

This linebacker will be the X-factor for the 49ers Week 12 battle with the Panthers on Monday Night Football at Levi Stadium.

Lamar Jackson and Jalen Hurts lead UPI senior sports writer Alex Butler's Top-20 fantasy football quarterback rankings for Week 12 of the 2025 season.

The Philadelphia Eagles (8-2) are still the only team above .500 in the NFC East after beating the Detroit Lions on Sunday ...

The San Francisco 49ers have a big game against the Carolina Panthers that will swing the playoff odds in a big way, ...

The Carolina Panthers are coming off a big win, which inevitably means there's going to be some sort of come-down. This is what happened in Week 10, and they lo ...

Get straight‑up moneyline picks from ChatGPT for every NFL Week 12 game, plus savvy analysis to bet the slate with confidence ...

New York Giants rookie Abdul Carter is eager to move past his public punishment for missing a walkthrough last week.

At first glance, the Carolina Panthers' rushing attack should be a problem for the San Francisco 49ers. Rico Dowdle is fourth ...