Over the past decade, several tumor-based predictors of cetuximab efficacy have been identified, yet most function as ...

As a proof of principle Bonnay et al (2020) started by investigating if Brat tumors have a metabolic profile that is different from normal brains. Using transcriptome data of both Brat‐depleted and ...

The regulation of unfolded protein response (UPR) sensors has been studied for over 20 years, but IRE1β has remained a mystery. IRE1β is highly expressed in goblet cells: specialized epithelial cells ...

The photoreceptors required for post‐translational regulation of CO have been characterized. Mutations in the genes encoding the photoreceptors phytochrome A (phyA) and cryptochrome 2 (cry2) delay ...

Sodium (Na +) is an alkali cation, which is not accumulated at large concentrations in most plant cells, in contrast to the alkali cation potassium (K +), which is an essential macronutrient for plant ...

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Mutations in fused in sarcoma (FUS) are a cause of familial amyotrophic lateral sclerosis (fALS). Patients carrying point mutations in the C‐terminus of FUS show neuronal cytoplasmic FUS‐positive ...

Processes vital to life such as respiration and photosynthesis critically depend on the availability of tetrapyrroles including hemes and chlorophylls. tRNA‐dependent catalysis generally is associated ...

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Many small lipophilic compounds in living cells can be modified by glycosylation. These processes can regulate the bioactivity of the compounds, their intracellular location and their metabolism. The ...

Many Wnts influence cell behavior by a conserved signaling cascade that promotes the stabilization and nuclear accumulation of β‐catenin (β‐cat), which then associates with TCF family members to ...